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He earned millions making billion-dollar companies.Usually when a large cap biopharma company has a big Phase III disaster, the top execs give it a quick midnight burial, issue a brief press release, put up with a few headlines, watch the market cap erode a bit and move on down the pipeline.RBC’s Randall Stanicky has been advocating a breakup for more than a year. He told me he was “pissed off” at them. The Gates Foundation was interested but told them they needed other investors. But BridgeBio also called Saunders a “dealmaker,” hinting that drug-launch advice isn’t all the company’s looking for from an executive known for pulling off big M&A.Then in October, the biotech was denied a merger deal by its Eidos unit to acquire the remaining 34% of Eidos shares it doesn’t already own, even though it raised its offer twice to the final tender equivalent to 1.5 BridgeBio shares for each piece of Eidos share. And Bob’s hit.”We'll e-mail you a link to set a new password. Scraggly and greying but no less opinionated at 52, he was mobbed at biotech conferences, having earned a reputation for crass wisdom and uncanny foresight, for making big bets on big ideas that changed medicine. 696.1k Followers, 1,585 Following, 220 Posts - See Instagram photos and videos from Brent Saunders (@brentlsaunders) So count him in on the crowd offering a thumbs up to failure, which will just drive more calls for quick change.Evercore ISI’s Umer Raffat spotlighted the possibility of a break into the green early today.Now, listening to Picker talk about T cells and antibodies and the curious biology of cytomegalovirus, Nelsen began wondering if it was time for another bet. Brent Saunders’ team gets hit with a PhIII disaster — and a growing mob of Allergan critics seizes the moment. Investors told them to come back with more data, pharmaceutical executives said they’re in the wrong game — too little money to be made fighting infectious disease. The obsession drove him to his first biotech investment in 1993, for an inhalable flu vaccine approved a decade later and still in use. Please note this link is one-time use only and is valid for only 24 hours.Phase 1 development of AMG 424, a CD38-CD3 XmAb antibody has been stopped, with rights reverting to Xencor.The terms of the deal include $120 million upfront for UCB, plus potential development and sales milestones, cost reimbursement and royalties totaling nearly $2 billion. By the look of Saunders’ appointment, it just may be.Sanofi's cost cuts are adding up, execs said in an update Wednesday. And he joined Actavis by way of an acquisition of Forest Laboratories, where he served as president and CEO.At his new job, Saunders hopes his experience “leading and growing global pharmaceutical companies” will help guide BridgeBio as it draws closer to commercializing its first drugs, he said in a statement. “It’s like the least trendy idea in the world,” Nelsen told me. Something like that would only further fuel the already blistering feedback Saunders’ been getting from some quarters.Three months after announcing the results of a landmark trial, Thrive Earlier Detection has raised $257 million to put their liquid biopsy cancer test into a pivotal trial.This wasn’t a popular opinion at the time. John Carroll Editor & Founder. And there was a cancer drug as well as an HIV program in the mix of the nixed.Unlock this story instantly and join 86,000+ biopharma pros reading Endpoints daily — and it's free.What do you charge for a Covid-19 vaccine? And it drove him to invest in CAR-T as a potential cure for HIV, years before it proved a wildly effective treatment for some cancers.GlaxoSmithKline R&D chief Hal Barron has tossed a lineup of COPD drugs out of the pipeline in the latest shift away from respiratory diseases.
He earned millions making billion-dollar companies.Usually when a large cap biopharma company has a big Phase III disaster, the top execs give it a quick midnight burial, issue a brief press release, put up with a few headlines, watch the market cap erode a bit and move on down the pipeline.RBC’s Randall Stanicky has been advocating a breakup for more than a year. He told me he was “pissed off” at them. The Gates Foundation was interested but told them they needed other investors. But BridgeBio also called Saunders a “dealmaker,” hinting that drug-launch advice isn’t all the company’s looking for from an executive known for pulling off big M&A.Then in October, the biotech was denied a merger deal by its Eidos unit to acquire the remaining 34% of Eidos shares it doesn’t already own, even though it raised its offer twice to the final tender equivalent to 1.5 BridgeBio shares for each piece of Eidos share. And Bob’s hit.”We'll e-mail you a link to set a new password. Scraggly and greying but no less opinionated at 52, he was mobbed at biotech conferences, having earned a reputation for crass wisdom and uncanny foresight, for making big bets on big ideas that changed medicine. 696.1k Followers, 1,585 Following, 220 Posts - See Instagram photos and videos from Brent Saunders (@brentlsaunders) So count him in on the crowd offering a thumbs up to failure, which will just drive more calls for quick change.Evercore ISI’s Umer Raffat spotlighted the possibility of a break into the green early today.Now, listening to Picker talk about T cells and antibodies and the curious biology of cytomegalovirus, Nelsen began wondering if it was time for another bet. Brent Saunders’ team gets hit with a PhIII disaster — and a growing mob of Allergan critics seizes the moment. Investors told them to come back with more data, pharmaceutical executives said they’re in the wrong game — too little money to be made fighting infectious disease. The obsession drove him to his first biotech investment in 1993, for an inhalable flu vaccine approved a decade later and still in use. Please note this link is one-time use only and is valid for only 24 hours.Phase 1 development of AMG 424, a CD38-CD3 XmAb antibody has been stopped, with rights reverting to Xencor.The terms of the deal include $120 million upfront for UCB, plus potential development and sales milestones, cost reimbursement and royalties totaling nearly $2 billion. By the look of Saunders’ appointment, it just may be.Sanofi's cost cuts are adding up, execs said in an update Wednesday. And he joined Actavis by way of an acquisition of Forest Laboratories, where he served as president and CEO.At his new job, Saunders hopes his experience “leading and growing global pharmaceutical companies” will help guide BridgeBio as it draws closer to commercializing its first drugs, he said in a statement. “It’s like the least trendy idea in the world,” Nelsen told me. Something like that would only further fuel the already blistering feedback Saunders’ been getting from some quarters.Three months after announcing the results of a landmark trial, Thrive Earlier Detection has raised $257 million to put their liquid biopsy cancer test into a pivotal trial.This wasn’t a popular opinion at the time. John Carroll Editor & Founder. And there was a cancer drug as well as an HIV program in the mix of the nixed.Unlock this story instantly and join 86,000+ biopharma pros reading Endpoints daily — and it's free.What do you charge for a Covid-19 vaccine? And it drove him to invest in CAR-T as a potential cure for HIV, years before it proved a wildly effective treatment for some cancers.GlaxoSmithKline R&D chief Hal Barron has tossed a lineup of COPD drugs out of the pipeline in the latest shift away from respiratory diseases.